The most expensive drugs
Revenues of some pharmaceutical companies are measured in billions. And sometimes, to get such a profit, firms need only to include in the range several products.
The list of expensive drugs is extensive. As a rule, pills for rare and mostly incurable diseases cost more than one thousand dollars or euros. Experts often claim that the cost of these drugs is seriously overestimated for a number of reasons, including the lack of competition.
The prices of biotechnological preparations for rare diseases continue to grow, flying into the stratosphere. There is no single price for the most expensive drugs in the world, and no one lists them.
The most expensive medicine in the world - 850 thousand dollars per dose!
Remember this name: Luxturna. From now on, it is the most expensive medication ever to travel through pharmacies.
No, this is not a cure for greed. This is actually, as they would say in Skolkovo, an “innovative drug”. So innovative that Spark Therapeutics, which developed Luxturna, was originally going to sell it for $ 1 million per single dose.
Luxturna is designed to cure a patient from an extremely bad disease - hereditary blindness. The drug cures blindness by the method of gene therapy (ultramodern and really effective direction in modern medicine, based on changes in the genetic apparatus of the patient's somatic cells).
After the insurance companies stated that a million is a brute force, an overwhelming burden for the budget, the price was reduced by 15 percent. But even that leaves Luxturna at the rank of the most expensive drug.
Testing has proven that Luxturna truly restores the vision of those who have a rare form of inherited blindness. It is estimated that about two thousand people are forced to live with this diagnosis in the United States.
How does this thing work? Fortunately, no self-suggestion - they say, since I paid 850 mowers, I just have to recover. After one injection of the drug, it acts like a virus on the retina of the eye and replaces the defective gene, after which the process of restoring vision begins. Injections will require two pieces (one per eye), the treatment of each eye will cost 425 thousand, which will give in sum those same 850 thousand.
At the same time, as experts who criticize greedy pharmacists note, the price is exorbitant, even by the standards of new-fangled gene therapy. For example, the most expensive gene drug against blood cancer costs 474 thousand dollars. Not a gift, but still much more modest than Luxturna.
The most lousy that experts say is that there is a real threat that when insurance companies start paying for such a fabulously expensive treatment, pharmaceutical corporations will be completely indulgent and start driving prices even higher!
Now, let's go over other drugs that are very expensive.
Soliris is a drug for patients who suffer from disorders of the immune system, in which a person begins to sleep in the blood ... blood cells begin to die (for what reasons it is not known for sure), which causes the kidneys, lungs, heart, brain to be destroyed. Without appropriate treatment, the life expectancy of such a patient is no more than 10 years. The medicine also allows you to suspend this process. Taking into account the fact that all over the world there are only 20,000 such patients, it becomes clear why the drug costs so much - a year of treatment costs $ 536 thousand, and the prices for a pack of pills start at 5,928 euros.
Naglazyme, which is used to correct disorders of metabolic processes. Such a disease quickly leads a person into a wheelchair. At the same time, the treatment allows almost immediately to see good results and positive dynamics - after the start of the course, patients begin to walk, motor progress is noted. In the world today, only 1,100 cases of a similar problem have been noted. Treatment with such a miracle cure will cost $ 485 thousand per year (i.e. approximately 3,800 euros per pack).
2,000 people in the world know what Hunter syndrome is, not by hearsay, because they themselves are sick. This disease is characterized by growth retardation, emerging breathing problems, thickening of the tongue, nostrils, and lips. It is believed to be more common at an early age - i.e. in children. Elaprase allows you to slow down the progression of the disease, returning deteriorated indicators of a person to a normal state. At the same time it should take 1 tablet per week. Packing cost - from 3750 euros.
Cinryze is a drug for the prevention of edema in patients with hereditary angioedema. This disease occurs due to the lack of certain enzymes in the blood and metabolic disorders. Since the phenomenon is unpredictable, swelling can occur at any time.As a result, patients have to lay out $ 350 thousand for annual treatment, or from 1948 euros - for each pack.
Myozyme, designed for patients with Pompe disease. This syndrome is caused by deficiency of alpha-glucosidase, which leads to the destruction of muscles, increase in heart size and breathing problems. Basically, the disease is more often diagnosed in childhood. Myozyme allows you to stop these processes and helps children breathe on their own.
The cost of annual treatment costs the parents $ 100 thousand. If a similar disease occurs in adults, then the course will be more expensive for them - $ 300 thousand per year, the price of packaging starts from 1000 euros.
Aldurazyme. Annual cost: $ 200,000 Manufacturer: Genzyme, BioMarin. This drug treats Hurler's syndrome (MPS I), which leads patients to a cessation of moral and physical development at the age of 4 years. Six hundred people in the world suffer from it.
Ceresim Annual cost: $ 200,000 Manufacturer: Genzyme. In Gaucher disease, fat accumulations accumulate in the spleen, liver, lungs, bone marrow, and sometimes in the brain, resulting in skeletal disorders, loss of lung and kidney functions. The drug replaces the enzyme that patients with Gaucher disease are missing.Around the world, there are 5,200 patients with this disease.
Fabrazyme. Annual cost: $ 200,000 Manufacturer: Genzyme. Fabry disease causes burning sensations, purple spots, heart enlargement and kidney problems. The number of patients with this disease exceeds 2,200 people worldwide. Seventh line among the most expensive drugs in the world 2015-2016.
Arcalyst. Annual cost: $ 250,000 Manufacturer: Regeneron. This drug treats Mackle-Wales syndrome, affecting 2,000 people worldwide. This syndrome causes recurring fevers, rashes, pains in the joints and kidneys.
Specialists often justify such high cost of vital medicines in that they are designed to overcome really rare and serious pathologies. Yes, for the chance of a partial, and in some cases complete recovery, it is not a pity for people to give any money. And the situation can change only if competitors enter the business - then the price of drugs may decrease, experts say.