The drug "Magnesium sulfate": use, indications, dosage and side effects
What is the drug "Magnesium sulfate"? The use of this tool is very wide. In this article we will describe in detail about the indications for use of the above-mentioned drug, its principle of action, properties and characteristics of use.
The drug “Magnesium sulfate”, the use of which we consider below, is an effective drug for oral use, as well as intravenous or intramuscular administration. The therapeutic effect of this drug depends on how it is used.
The composition of the tool
The drug "Magnesium sulfate" as an active ingredient includes ions of the sulfate group and magnesium ions. Such a chemical compound is characterized by a fairly wide range of effects on the human body.In medical practice, "magnesium sulfate" has been used for a long time. That is why all of its properties have been carefully studied, confirmed empirically and scientifically. The drug has various effects, and therefore is widely used by specialists to eliminate various pathologies.
The drug "Magnesium sulfate" has antiarrhythmic, anticonvulsant, hypotensive, vasodilator, tocolytic, sedative and antispasmodic properties, thanks to which it is actively used to treat many diseases. For example, this tool is indispensable in gynecology: it quickly relaxes the muscles of the uterus (which is necessary in case of threatened abortion), relieves seizures, lowers blood pressure, etc.
In addition to all the above properties, this drug has choleretic and laxative effects. The laxative effect of this remedy is due to its poor absorbability, which ultimately leads to the creation of a fairly high pressure (osmotic) in the intestine, which contributes to the accumulation of fluid, the dilution of its contents and increased peristalsis.As for the choleretic action, this is due to the reflex effect of the drug on the mucous membrane of the duodenum.
Other medication names
The drug "Magnesium sulfate" has several names. So, in pharmacy chains you can purchase magnesium sulphate, English or bitter salt, magnesium sulphate heptahydrate and magnesia. These names are very often used to refer to the presented funds.
Currently, the drug is available in two dosage forms, namely, in the form of a powder and a solution in ampoules. The powder can be purchased in packs of 50, 25, 20 and 10 g. It is intended for dilution in water in order to obtain a suspension, which can later be taken orally. As for the solution in ampoules, this tool is available in 30, 20 and 10 ml in two possible concentrations - 25 and 20%. In other words, 100 ml of this preparation contains 25 and 20 g of magnesium sulfate, respectively. It should be particularly noted that the solution and the powder include only the named chemical. That is, there are no auxiliary components in this tool.
After ingestion, a small part of the drug, absorbed into the blood, is excreted by the kidneys. Thus, the powder "Magnesia" has not only a laxative, but also a diuretic effect. Quite often, this tool is taken in case of poisoning with salts of heavy metals. This appointment is due to the fact that the main active ingredient of the drug plays the role of an antidote. It binds heavy fractions of metals, and then immediately removes them from the body along with feces. The effect after ingestion develops in about 30-180 minutes, and lasts at least 3-7 hours.
Indications for oral administration
Powder intended for the preparation of suspensions is prescribed for:
Indications for intravenous and intramuscular injections
The drug "Magnesium sulfate" intravenously and intramuscularly used with:
- the threat of preterm birth;
- epileptic syndrome;
- urinary retention.
The drug "Magnesium sulfate": application
Before ingestion, the powder “Magnesium sulfate” must be dissolved in 100 milliliters of warm water. To get a laxative effect, as a single dose, adults are recommended to use the contents of one sachet.If the drug is prescribed to the child, then its quantity (in gr.) Should correspond to the age of the baby. To obtain a choleretic effect, a 20-25% solution of the above-mentioned drug should be taken orally three times a day, 15 ml each. To clean the gastric tract from heavy metal salts, it is recommended to wash with a 1% solution. In this case, the daily dose of the drug for adults should not exceed 40 grams.
Magnesium sulfate medication intramuscularly
Intramuscular administration of the drug in question is most often used, but not in cases where it is necessary to quickly remove a hypertensive crisis, eliminate eclampsia, or stop seizures in the mother. The substance in the form of a 20-25% solution should be injected into the muscle twice a day. Thus, each injection has about 5–20 milliliters of magnesia (depending on the degree of pathological symptoms). Course duration is 15-25 days.
Intravenous administration of this drug is used only in cases where it is necessary to quickly arrest the patient’s acute condition that threatens his life (for example, in myocardial infarction, hypertensive crisis, severe eclampsia, etc.).In such cases, you should apply a 20 percent solution in an amount of 5-20 milliliters (depending on the severity of the patient's condition). As a rule, intravenous administration of magnesia is carried out 1 or 2 times a day. To quickly remove the pain caused by spasm of the sphincter of the bladder, you must simultaneously enter 10 ml of a 5% solution of magnesium sulfate. In severe poisoning with barium salts and metals, 5 or 10 ml of a 10% preparation should be used. This is necessary in order to bind, and later neutralize toxic substances that have already entered the bloodstream.
If the drug “Magnesium sulfate”, the use of which was described above, must be used for a long time, then the patient’s blood pressure, heart function, kidney function, tendon reflexes and respiratory rate should be monitored. In addition, if a person requires the simultaneous intake of both calcium and magnesium, then it is recommended to inject them into different veins.
The drug "Magnesium sulfate" may contribute to the emergence of undesirable reactions such as:
- electrolyte imbalance, manifested in the form of confusion, arrhythmia, fatigue, seizures and asthenia;
- exacerbation of diseases of the digestive tract, including the appearance of diarrhea, vomiting, nausea, flatulence, thirst, etc.